Article
TreeDT: tree pattern mining for gene mapping.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Sevon Petteri, Toivonen Hannu, Ollikainen Vesa
Abstract excerpt
We describe TreeDT, a novel association-based gene mapping method. Given a set of disease-associated haplotypes and a set of control haplotypes, TreeDT predicts likely locations of a disease susceptibility gene. TreeDT extracts, essentially in the form of haplotype trees, information about historical recombinations in the population: A haplotype tree constructed at a given chromosomal location is an estimate of...
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