Article
Mining associations between genetic markers, phenotypes, and covariates.
Genetic epidemiology - 1 Jan 2001
Sevon P, Ollikainen V, Onkamo P, Toivonen H T, Mannila H, Kere J
Abstract excerpt
We used Haplotype Pattern Mining, HPM [Toivonen et al., Am J Hum Genet 67:133-45, 2000], for gene localization in Genetic Analysis Workshop (GAW) 12 isolate data. In HPM, association is analyzed by searching all trait-associated haplotype patterns. Data mining algorithms are utilized to make the search efficient. The strength of the haplotype-trait associations is measured by a linear model, into which a...
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