Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of decreased mitochondrial DNA content with ovarian cancer progression

1 Oct 2006

Abstract excerpt

Mitochondrial DNA (mtDNA) content in ovarian carcinomas was assessed by quantitative PCR. Results show that mtDNA content in tumour cell was significantly higher than that in normal ovary. Change in mtDNA content was not related with patients' age or tumour stages. However, the average mtDNA copy number in pathological low-grade tumours was over two-fold higher than that in high-grade carcinomas (P=0.012)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Ovarian cancer diagnosis and treatment
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17047655
DOI: 10.1038/sj.bjc.6603377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of decreased mitochondrial DNA content with ovarian cancer progressionPMID 17047655Read ↗

Association of decreased mitochondrial DNA content with the progression of colorectal cancerSemantic proximity Read ↗

High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas.Semantic proximity Read ↗

Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patientsSemantic proximity Read ↗

Mitochondrial genome instability and mtDNA depletion in human cancers.Semantic proximity Read ↗

Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancerSemantic proximity Read ↗

Circulating Mitochondrial DNA is Linked to Progression and Prognosis of Epithelial Ovarian CancerSemantic proximity Read ↗

Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapySemantic proximity Read ↗

High frequency of mitochondrial genome instability in human endometrial carcinomas.Semantic proximity Read ↗

Impact of platinum on the whole mitochondrial genome of ovarian carcinomas both in vivo and in vitro.Semantic proximity Read ↗

Low copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in early-stage laryngeal cancer patientsSemantic proximity Read ↗

Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survivalSemantic proximity Read ↗

Lower mitochondrial DNA copy number in peripheral blood leukocytes increases the risk of endometrial cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.