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Article

Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice.

Acta histochemica - 1 Jan 2007

Fabrizio Rodella Luigi, Bonomini Francesca, Rezzani Rita, Tengattini Sandra, Hayek Tony, Aviram Michael, Keidar Shlomo, Coleman Raymond, Bianchi Rossella

Abstract excerpt

The aim of the present study was to analyze the early events in atherogenesis and the role of pro- or anti-atherosclerotic proteins in the development of atherosclerotic lesions. We used apolipoprotein E-deficient (E(0)) mice that spontaneously develop hypercholesterolemia and atherosclerotic lesions in the aorta in a time-dependent manner. Aortas of mice aged 6, 8, 10 and 12 weeks were examined to determine...

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Source

Identifiers

PMID: 17046051
DOI: 10.1016/j.acthis.2006.08.002

Genes

MMP2
NOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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