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Article

Expression and loss of alleles in cultured mouse embryonic fibroblasts and stem cells carrying allelic fluorescent protein genes.

BMC molecular biology - 16 Oct 2006

Larson Jon S, Yin Moying, Fischer Jared M, Stringer Saundra L, Stringer James R

Abstract excerpt

BACKGROUND: Loss of heterozygosity (LOH) contributes to many cancers, but the rate at which these events occur in normal cells of the body is not clear. LOH would be detectable in diverse cell types in the body if this event were to confer an obvious cellular phenotype. Mice that carry two different fluorescent protein genes as alleles of a locus would seem to be a useful tool for addressing this issue because...

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Identifiers

PMID: 17042952
DOI: 10.1186/1471-2199-7-36
PMCID: PMC1621078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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