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Article

A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity.

DNA repair - 1 Jan 2015

Uringa Evert-Jan, Baldeyron Céline, Odijk Hanny, Wassenaar Evelyne, van Cappellen Wiggert A, Maas Alex, Hoeijmakers Jan H J, Baarends Willy M, Kanaar Roland, Essers Jeroen

Abstract excerpt

Accurate DNA double-strand break repair through homologous recombination is essential for preserving genome integrity. Disruption of the gene encoding RAD51, the protein that catalyzes DNA strand exchange during homologous recombination, results in lethality of mammalian cells. Proteins required for homologous recombination, also play an important role during DNA replication. To explore the role of RAD51 in DNA...

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Share to DNA Breaks, Double-Stranded
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25463395
DOI: 10.1016/j.dnarep.2014.11.002

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity.PMID 25463395Read ↗

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