Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Truncation analysis of several DR binding epitopes.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 1991

O'Sullivan D, Sidney J, Del Guercio M F, Colón S M, Sette A

Abstract excerpt

Peptide regions crucial for binding to four different DR alleles (DR1, DR2, DR5, and DR52a) have been localized in five unrelated DR binding peptides (dynorphin 1-13, sperm whale myoglobin 132-153, influenza hemagglutinin 307-319, pigeon cytochrome c 88-104, and tetanus toxoid 830-843) by testing panels of truncated analogs for DR binding. It was found that in most cases, different DR alleles recognize almost...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Hemagglutinins, Viral

Share to HLA-DR Antigens

Share to Molecular Sequence Data

Share to Peptide Fragments

Source

Identifiers

PMID: 1704034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Truncation analysis of several DR binding epitopes.PMID 1704034Read ↗

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.Semantic proximity Read ↗

Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides.Semantic proximity Read ↗

Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition.Semantic proximity Read ↗

An HLA-DRB alpha-helix motif shared by DR11 and DR8 alleles is implicated in the pluriallelic restriction of peptide-specific T-cell lines.Semantic proximity Read ↗

HLA-DR restricted peptide candidates for bee venom immunotherapy.Semantic proximity Read ↗

The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86.Semantic proximity Read ↗

Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides.Semantic proximity Read ↗

Role of HLA-DP in the Presentation of Epitopes from the Truncated Bacterial PE38 Immunotoxin.Semantic proximity Read ↗

Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles.Semantic proximity Read ↗

Functional dissection of the serological DR LYGUE and genotypic DRB1*1303 specificities using a tetanus toxin-specific T-cell clone.Semantic proximity Read ↗

Epitopes for human CD4<sup>+</sup> cells on diphtheria toxin: Structural features of sequence segments forming epitopes recognized by most subjectsSemantic proximity Read ↗

Microvariation creates significant functional differences in the DR3 molecules.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.