Article
Truncation analysis of several DR binding epitopes.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 1991
O'Sullivan D, Sidney J, Del Guercio M F, Colón S M, Sette A
Abstract excerpt
Peptide regions crucial for binding to four different DR alleles (DR1, DR2, DR5, and DR52a) have been localized in five unrelated DR binding peptides (dynorphin 1-13, sperm whale myoglobin 132-153, influenza hemagglutinin 307-319, pigeon cytochrome c 88-104, and tetanus toxoid 830-843) by testing panels of truncated analogs for DR binding. It was found that in most cases, different DR alleles recognize almost...
Topics
- Alleles
- Amino Acid Sequence
- Cell Line, Transformed
- Dynorphins
- Epitopes
- HLA-DR Antigens
- Hemagglutinin Glycoproteins, Influenza Virus
- Hemagglutinins, Viral
- Humans
- Molecular Sequence Data
- Myoglobin
