Article
Functional dissection of the serological DR LYGUE and genotypic DRB1*1303 specificities using a tetanus toxin-specific T-cell clone.
Tissue antigens - 1 Sept 1993
Martínez-Soria E, Tiercy J M, Beffy P, Taban-Marín P, Jaques D, Bétuel H, Jeannet M, Mach B, Irlé C
Abstract excerpt
The DRB1 sequence of the homozygous cell line HAG (DR13-DwHAG-DQ7) represents a new DRB allele assigned DRB1*1103, whereas its DRB3 sequence corresponds to the previously described DRB3*0101 (DR52a) allele. The DRB1*1303 gene product is undetectable by current sera used in routine serology typing. We report here direct evidence that the MHC molecule encoded by the DRB1*1303 gene is functional in antigen...
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