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Article

Epitopes for human CD4<sup>+</sup> cells on diphtheria toxin: Structural features of sequence segments forming epitopes recognized by most subjects

1 Dec 1995

Abstract excerpt

The sequence regions of diphtheria toxin (DTX) recognized by CD4+ T cells of seven healthy humans of different major histocompatibility complex haplotypes were identified. Overlapping synthetic peptides, screening the DTX sequence, were used to test in proliferation assays unselected blood CD4+ cells, or DTX-specific CD4+ lines propagated by stimulation with DTX of blood mononuclear cells. Blood CD4+ cells and...

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Identifiers

PMID: 8566002
DOI: 10.1002/eji.1830251202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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