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Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats.

Transplantation - 15 Oct 2006

Xu Leyan, Yan Jun, Chen David, Welsh Annie M, Hazel Thomas, Johe Karl, Hatfield Glen, Koliatsos Vassilis E

Abstract excerpt

BACKGROUND: Experimental therapeutics for degenerative and traumatic diseases of the nervous system have been recently enriched with the addition of neural stem cells (NSCs) as alternatives to fetal tissues for cell replacement. Neurodegenerative diseases present the additional problem that cell death signals may interfere with the viability of grafted cells. The adult spinal cord raises further challenges for...

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Source

Identifiers

PMID: 17038899
DOI: 10.1097/01.tp.0000235532.00920.7a

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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