Article
Olfactory ensheathing cell transplantation into spinal cord prolongs the survival of mutant SOD1(G93A) ALS rats through neuroprotection and remyelination.
Anatomical record (Hoboken, N.J. : 2007) - 1 May 2011
Li Ying, Bao Jianling, Khatibi Nikan H, Chen Lin, Wang Hongmei, Duan Yaokui, Huang Hongyun, Zhou Changman
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a progressively fatal, incurable, neurodegenerative disorder. In this study, we investigated whether olfactory ensheathing cells (OEC) transplantation could provide protection to motor neurons and enable remyelination in mutant SOD1(G93A) transgenic rats with ALS. Seventy-two rats were divided into four groups: SOD1(G93A) rats (n = 20); medium+SOD1(G93A) rats (n = 20);...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.