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Article

Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability.

International journal of cancer - 15 Dec 2006

Pinyol Magda, Salaverria Itziar, Bea Silvia, Fernández Verónica, Colomo Lluís, Campo Elías, Jares Pedro

Abstract excerpt

DNA licensing is a crucial process for chromosome replication control. Deregulation of the licensing factors Cdt1, Cdc6 and the licensing inhibitor geminin has been associated with DNA replication defects and chromosomal instability. We examined the expression of these factors, in mantle cell lymphoma (MCL) and non-neoplastic lymphoid samples, and analysed the potential role of their deregulation in genomic...

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Identifiers

PMID: 17036332
DOI: 10.1002/ijc.22146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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