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Article

tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile.

Journal of clinical microbiology - 1 Jan 2007

Curry Scott R, Marsh Jane W, Muto Carlene A, O'Leary Mary M, Pasculle A William, Harrison Lee H

Abstract excerpt

Severe Clostridium difficile associated disease is associated with outbreaks of the recently described BI/NAP1 epidemic clone. This clone is characterized by an 18-bp deletion in the tcdC gene and increased production of toxins A and B in vitro. TcdC is a putative negative regulator of toxin A&B production. We characterized tcdC genotypes from a collection of C. difficile isolates from a hospital that experienced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17035492
DOI: 10.1128/JCM.01599-06
PMCID: PMC1828959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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