Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences

14 May 2008

Abstract excerpt

The reported incidence and mortality of Clostridium difficile-associated disease has increased significantly, which in part is likely to be due to the emergence of a new, highly virulent strain in North America and Europe. This epidemic strain, referred to as BI/NAP1/027, has increased virulence, attributed to overexpression of the two toxin-encoding genes, tcdA and tcdB, which may be due to truncation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Clostridium difficile and Clostridium perfringens research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18480336
DOI: 10.1099/jmm.0.47743-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequencesPMID 18480336Read ↗

tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile.Semantic proximity Read ↗

Genome sequence and characterization of a hypervirulent BI/NAP1/027 <i>Clostridioides difficile</i> (CDC20121308)Semantic proximity Read ↗

Variations in Virulence and Molecular Biology among Emerging Strains of Clostridium difficileSemantic proximity Read ↗

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.Semantic proximity Read ↗

Prophage-Stimulated Toxin Production in Clostridium difficile NAP1/027 LysogensSemantic proximity Read ↗

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.Semantic proximity Read ↗

The Hypervirulent Strain of Clostridium Difficile: NAP1/B1/027 - A Brief OverviewSemantic proximity Read ↗

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficileSemantic proximity Read ↗

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.Semantic proximity Read ↗

Whole genome analysis reveals new insights into the molecular characteristics of Clostridioides difficile NAP1/BI/027/ST1 clinical isolates in the People’s Republic of ChinaSemantic proximity Read ↗

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) <i>Clostridioides difficile</i>Semantic proximity Read ↗

Sequence variation in tcdA and tcdB of Clostridium difficile: ST37 with truncated tcdA is a potential epidemic strain in China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.