Article

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) <i>Clostridioides difficile</i>

2023-01-12

Abstract excerpt

Clostridioides difficile (C. difficile) , a leading cause of nosocomial infection, produces toxins that damage the colonic epithelium and results in colitis that varies from mild to fulminant. Variation in disease severity is poorly understood and has been attributed to host factors (age, immune competence and intestinal microbiome composition) and/or virulence differences between C. difficile strains, with some,...

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Literature Corpus work: 20746cd9-6562-52b6-a8fd-32edb880c44c
DOI: 10.1101/2023.01.12.523823

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