Article
Immune activation and T cell subset abnormalities in circulation of patients with recently diagnosed type I diabetes mellitus.
Clinical and experimental immunology - 1 Aug 1990
al-Kassab A S, Raziuddin S
Abstract excerpt
The peripheral blood lymphocytes from patients with insulin-dependent diabetes mellitus (IDDM) and healthy controls were analysed for the HLA-DR+, interleukin-2 receptor-positive (IL-2R+) activating antigens, and for CD45R+ and CDw29+ subsets from the purified CD4+ and CD8+ T cells populations. Patients with IDDM had an increased percentage of HLA-DR+ and IL-2R+ cells in both CD4+ and CD8+ T cells. However, the...
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