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Article

Down syndrome, autoimmunity and T regulatory cells.

Clinical and experimental immunology - 1 Sept 2012

Pellegrini F P, Marinoni M, Frangione V, Tedeschi A, Gandini V, Ciglia F, Mortara L, Accolla R S, Nespoli L

Abstract excerpt

Autoimmune diseases are more represented in Down syndrome (DS) individuals compared to chromosomally normal people. Natural T regulatory cells (nT(reg) ) have been considered to be primary in the role of controlling the intensity and targets of the immune response. We have investigated the phenotypical and functional alteration of nT(reg) in a group of DS people. The phenotypical characteristic of T(reg) cells of...

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Identifiers

PMID: 22861363
DOI: 10.1111/j.1365-2249.2012.04610.x
PMCID: PMC3445000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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