Article

Discovery of functional non-coding conserved regions in the α-synuclein gene locus

2014-12-08

Abstract excerpt

Several single nucleotide polymorphisms (SNPs) and the Rep-1 microsatellite marker of the α-synuclein ( SNCA ) gene have consistently been shown to be associated with Parkinson’s disease, but the functional relevance is unclear. Based on these findings we hypothesized that conserved cis-regulatory elements in the SNCA genomic region regulate expression of SNCA , and that SNPs in these regions could be functiona...

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Literature Corpus work: 2a57c317-356e-5fbf-9a7a-f62eafb54e61
DOI: 10.12688/f1000research.3281.2

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