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Article

A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.

Structure (London, England : 1993) - 1 Oct 2006

Yuan Yu-Ren, Pei Yi, Chen Hong-Ying, Tuschl Thomas, Patel Dinshaw J

Abstract excerpt

Argonaute proteins are key components of the RNA-induced silencing complex (RISC). They provide both architectural and catalytic functionalities associated with small interfering RNA (siRNA) guide strand recognition and subsequent guide strand-mediated cleavage of complementary mRNAs. We report o...

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Identifiers

PMID: 17027504
DOI: 10.1016/j.str.2006.08.009
PMCID: PMC4692372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17027504-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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