Article
The rs9509 polymorphism of MMP-9 is associated with risk of hemorrhage in brain arteriovenous malformations.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Sept 2012
Sun Bing, Qiu Huijia, Zhao Fan, Qiao Nidan, Fan Weiwei, Lu Daru, Chen Hongyan, Hu Jin, Fu Chaowei, Zhou Liangfu, Gu Yuxiang, Zhao Yao, Mao Ying
Abstract excerpt
We examined whether single nucleotide polymorphisms (SNP) of the matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 4 (TIMP-4) genes are associated with risk of intracranial hemorrhage (ICH) among patients with brain arteriovenous malformation (BAVM). For 311 Chinese patients with BAVM, we performed genotyping analysis for 11 selected SNP of MMP-9 and TIMP-4 using the MassARRAY...
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