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The rs522616 polymorphism in the matrix metalloproteinase-3 (MMP-3) gene is associated with sporadic brain arteriovenous malformation in a Chinese population.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Dec 2010

Zhao Yao, Li Peiliang, Fan Weiwei, Chen Dan, Gu Yuxiang, Lu Daru, Zhao Fan, Hu Jin, Fu Chaowei, Chen Xiancheng, Zhou Liangfu, Mao Ying

Abstract excerpt

In this study, we investigated the association between common variants in the matrix metalloproteinase-3 (MMP-3) gene and the risk of developing sporadic brain arteriovenous malformation (BAVM). We performed genotyping analyses for five single nucleotide polymorphisms (SNPs) in MMP-3 in a case-control study involving 319 Chinese patients with BAVM and 333 Chinese controls. The association between MMP-3 genotypes...

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PMID: 20822909
DOI: 10.1016/j.jocn.2010.04.023

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