Article
Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice.
Molecular and cellular biology - 1 Oct 2002
Schymeinsky Jürgen, Nedbal Sabine, Miosge Nicolai, Pöschl Ernst, Rao Cherie, Beier David R, Skarnes William C, Timpl Rupert, Bader Bernhard L
Abstract excerpt
Nidogens are highly conserved proteins in vertebrates and invertebrates and are found in almost all basement membranes. According to the classical hypothesis of basement membrane organization, nidogens connect the laminin and collagen IV networks, so stabilizing the basement membrane, and integrate other proteins. In mammals two nidogen proteins, nidogen-1 and nidogen-2, have been discovered. Nidogen-2 is...
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