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Article

Why study human limb malformations?

Journal of anatomy - 1 Jan 2003

Wilkie Andrew O M

Abstract excerpt

Congenital limb malformations occur in 1 in 500 to 1 in 1000 human live births and include both gross reduction defects and more subtle alterations in the number, length and anatomy of the digits. The major causes of limb malformations are abnormal genetic programming and intra-uterine disruption to development. The identification of causative gene mutations is important for genetic counselling and also provides...

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Identifiers

PMID: 12587917
DOI: 10.1046/j.1469-7580.2003.00130.x
PMCID: PMC1571054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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