Article
Unraveling the genetics of systemic lupus erythematosus.
Springer seminars in immunopathology - 1 Oct 2006
Harley John B, Kelly Jennifer A, Kaufman Kenneth M
Abstract excerpt
The capacity to locate polymorphisms on a virtually complete map of the human genome coupled with the ability to accurately evaluate large numbers (by historical standards) of genetic markers has led to gene identification in complex diseases, such as systemic lupus erythematosus (SLE or lupus). While this is a phenotype with enormous clinical variation, the twin studies and the observed familial aggregation,...
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