Article
The genetics of systemic lupus erythematosus: putting the pieces together.
Genes and immunity - 1 Oct 2002
Kelly J A, Moser K L, Harley J B
Abstract excerpt
With lambda(s) estimates of 10 to 20 and other evidence of familial aggregation, as well as a monozygotic twin concordance rate >20, systemic lupus erythematosus (SLE) would appear to be a very promising phenotype using modern genetic approaches. Indeed, genetic associations are already known at numerous candidate loci including various HLA alleles, complement component genes, Fcgamma receptors, and others, and...
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