Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers.

doi:10.1016/0014-4827(90)90007-w

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Article

Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers.

Experimental cell research - 1 Dec 1990

Orlow S J, Chakraborty A K, Boissy R E, Pawelek J M

Abstract excerpt

Retinoic acid, hexamethylene bisacetamide, sodium butyrate, and dimethylsulfoxide, four compounds which modulate phenotypic expression in a variety of neoplastic cell lines, all inhibited the induction of tyrosinase activity and melanogenesis by the combination of melanocyte-stimulating hormone a...

Topics

1-Methyl-3-isobutylxanthine
Acetamides
Animals
Butyrates
Butyric Acid
Cell Transformation, Neoplastic
Dimethyl Sulfoxide
Indolequinones
Indoles
Melanins
Melanocyte-Stimulating Hormones
Melanocytes
Melanoma, Experimental
Mice
Microscopy, Electron
Monophenol Monooxygenase
Phenotype
Quinones

Source

Open in PubMed

Identifiers

PMID: 1701721
DOI: 10.1016/0014-4827(90)90007-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1701721-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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