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Article

Melanotropic activity of gamma MSH peptides in melanoma cells.

Life sciences - 1 Jan 1992

Slominski A, Costantino R, Wortsman J, Paus R, Ling N

Abstract excerpt

We studied the pigmentary activity of the peptides gamma 1, gamma 2 and gamma 3 melanocyte stimulating hormone (MSH), which differ in the structure of their C-termini, using hamster and mouse melanoma cell lines responsive to beta-MSH by increasing tyrosinase activity. Gamma 1-MSH alone or in combination with beta-MSH had no effect on either cell line. Gamma 2-MSH alone was biologically inactive but potentiated...

Topics

Amino Acid Sequence
Animals
Cattle
Cricetinae
In Vitro Techniques
Melanocyte-Stimulating Hormones
Melanoma
Mice
Molecular Sequence Data
Monophenol Monooxygenase
Phenotype
Pigmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

Source

Identifiers

PMID: 1556905
DOI: 10.1016/0024-3205(92)90347-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1556905-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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