Article
Melanotropic activity of gamma MSH peptides in melanoma cells.
Life sciences - 1 Jan 1992
Slominski A, Costantino R, Wortsman J, Paus R, Ling N
Abstract excerpt
We studied the pigmentary activity of the peptides gamma 1, gamma 2 and gamma 3 melanocyte stimulating hormone (MSH), which differ in the structure of their C-termini, using hamster and mouse melanoma cell lines responsive to beta-MSH by increasing tyrosinase activity. Gamma 1-MSH alone or in combination with beta-MSH had no effect on either cell line. Gamma 2-MSH alone was biologically inactive but potentiated...
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