Article
Induced melanin reduces mutations and cell killing in mouse melanoma.
Photochemistry and photobiology - 1 Mar 1997
Li W, Hill H Z
Abstract excerpt
When melanin absorbs light energy, it can produce potentially damaging active oxygen species. There is little doubt that constitutive pigment in dark-skinned individuals is photoprotective against skin cancer, but induced pigment-as in tanning-may not be. The first step in cancer induction is mutation in DNA. The most suitable systems for evaluating the role of melanin are those in which pigment can be varied and...
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