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Article

Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients

1 Nov 2006

Abstract excerpt

The ECT2 (epithelial cell transforming sequence 2) proto-oncogene encodes a guanine nucleotide exchange factor for Rho GTPases, and regulates cytokinesis. ECT2 plays a critical role in Rho activation during cytokinesis, and thus may play a role in the pathogenesis of glioma. In this study, we investigated relationships between ECT2 expression, tumor histology, and prognosis in glioma patients. ECT2 mRNA...

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PMID: 17016598
DOI: 10.3892/or.16.5.1093

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