Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival.

Genes - 17 Oct 2022

Xiong Zhang, Wu Shuai, Li Feng-Jiao, Luo Chen, Jin Qiu-Yan, Connolly Ian David, Hayden Gephart Melanie, You Linya

Abstract excerpt

Background: GBM astrocytes may adopt fetal astrocyte transcriptomic signatures involved in brain development and migration programs to facilitate diffuse tumor infiltration. Our previous data show that ETS variant 6 (ETV6) is highly expressed in human GBM and fetal astrocytes compared to normal mature astrocytes. We hypothesized that ETV6 played a role in GBM tumor progression. Methods: Expression of ETV6 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Glioma

Share to NF-kappa B

Share to Phenotype

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins c-akt

Source

Open in PubMed Open full text

Identifiers

PMID: 36292767
DOI: 10.3390/genes13101882
PMCID: PMC9656946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival.PMID 36292767Read ↗

STAT6 expression in glioblastoma promotes invasive growthSemantic proximity Read ↗

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferationSemantic proximity Read ↗

LY6K promotes glioblastoma tumorigenicity via CAV-1–mediated ERK1/2 signaling enhancementSemantic proximity Read ↗

E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and functionSemantic proximity Read ↗

PVT1 promotes proliferation and macrophage immunosuppressive polarization through STAT1 and CX3CL1 regulation in glioblastoma multiformeSemantic proximity Read ↗

Impact of endogenous viral elements on glioma clinical phenotypes by inducing OCT4 in the host.Semantic proximity Read ↗

E26 transformation-specific variant 4 as a tumor promotor in human cancers through specific molecular mechanismsSemantic proximity Read ↗

PEA3 Transcription Factors, Role in Invasion, Proliferation and Radioresistance of Glioblastoma Stem CellsSemantic proximity Read ↗

Loss of ELAVL2 is associated with aggressive mesenchymal transition in glioblastomaSemantic proximity Read ↗

Identification of ETV5 as a prognostic marker related to epigenetic modification in pan-cancer and facilitates tumor progression in hepatocellular carcinomaSemantic proximity Read ↗

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated PathwaySemantic proximity Read ↗

ETV6 gene aberrations in non-haematological malignancies: A review highlighting ETV6 associated fusion genes in solid tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.