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Article

TWIST is expressed in human gliomas and promotes invasion.

Neoplasia (New York, N.Y.) - 1 Sept 2005

Elias Maria C, Tozer Kathleen R, Silber John R, Mikheeva Svetlana, Deng Mei, Morrison Richard S, Manning Thomas C, Silbergeld Daniel L, Glackin Carlotta A, Reh Thomas A, Rostomily Robert C

Abstract excerpt

TWIST, a basic helix-loop-helix (bHLH) transcription factor that regulates mesodermal development, has been shown to promote tumor cell metastasis and to enhance survival in response to cytotoxic stress. Our analysis of rat C6 glioma cell-derived cDNA revealed TWIST expression, suggesting that the gene may play a role in the genesis and physiology of primary brain tumors. To further delineate a possible oncogenic...

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Source

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Identifiers

PMID: 16229805
DOI: 10.1593/neo.04352
PMCID: PMC1501937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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