Article
Up-regulation of EphA2 and down-regulation of EphrinA1 are associated with the aggressive phenotype and poor prognosis of malignant glioma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2010
Li Xia, Wang Li, Gu Jian-Wen, Li Bing, Liu Wei-Ping, Wang Yan-Gang, Zhang Xiang, Zhen Hai-Ning, Fei Zhou
Abstract excerpt
Malignant gliomas display over-expression of the receptor tyrosine kinase EphA2. However, expression levels of the EphA2 ligand, EphrinA1, have not been fully elucidated. Seventy-eight patients with primary gliomas were included in this study who underwent surgical resection, radiation, and chemo...
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