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ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer.

Cancer gene therapy - 1 Jan 2023

Liu Xiaoli, Zhang Junhua, Ju Shuang, Liu Lu, Sun Yu, Guo Lingyu, Zhen Qianwei, Han Sai, Lu Wei, Zhang Youzhong

Abstract excerpt

Epithelial cell transforming sequence 2 (ECT2) is expressed at high levels in various malignancies and contributes to malignant phenotypes in cancers. However, ECT2 is still not fully understood regarding its function and carcinogenic mechanism in cervical cancer. This research indicated that ECT2 expression was elevated in cervical cancer based on bioinformatics analysis and clinical specimens. Experiments in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36056253
DOI: 10.1038/s41417-022-00525-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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