Article
Epithelial membrane protein-2 (EMP2) activates Src protein and is a novel therapeutic target for glioblastoma.
The Journal of biological chemistry - 16 May 2014
Qin Yu, Fu Maoyong, Takahashi Masamichi, Iwanami Akio, Kuga Daisuke, Rao Rajiv G, Sudhakar Deepthi, Huang Tiffany, Kiyohara Meagan, Torres Kathleen, Dillard Christen, Inagaki Akihito, Kasahara Noriyuki, Goodglick Lee, Braun Jonathan, Mischel Paul S, Gordon Lynn K, Wadehra Madhuri
Abstract excerpt
Despite recent advances in molecular classification, surgery, radiotherapy, and targeted therapies, the clinical outcome of patients with malignant brain tumors remains extremely poor. In this study, we have identified the tetraspan protein epithelial membrane protein-2 (EMP2) as a potential targ...
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