Article
Suppression of putative tumour suppressor gene GLTSCR2 expression in human glioblastomas.
The Journal of pathology - 1 Oct 2008
Kim Y-J, Cho Y-E, Kim Y-W, Kim J-Y, Lee S, Park J-H
Abstract excerpt
Glioma tumour-suppressor candidate region gene 2 (GLTSCR2/PICT-1) is localized within the well-known 1.4 Mb tumour-suppressive region of chromosome 19q, which is frequently altered in various human tumours, including diffuse gliomas. Aside from its chromosomal localization, several lines of evidence, including PTEN-phosphorylating and cell-killing activities, suggests that GLTSCR2 participates in the suppression...
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