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Article

Physiological analysis of the stringent response elicited in an extreme thermophilic bacterium, Thermus thermophilus.

Journal of bacteriology - 1 Oct 2006

Kasai Koji, Nishizawa Tomoyasu, Takahashi Kosaku, Hosaka Takeshi, Aoki Hiroyuki, Ochi Kozo

Abstract excerpt

Guanosine tetraphosphate (ppGpp) is a key mediator of stringent control, an adaptive response of bacteria to amino acid starvation, and has thus been termed a bacterial alarmone. Previous X-ray crystallographic analysis has provided a structural basis for the transcriptional regulation of RNA polymerase activity by ppGpp in the thermophilic bacterium Thermus thermophilus. Here we investigated the physiological...

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Identifiers

PMID: 17015650
DOI: 10.1128/JB.00574-06
PMCID: PMC1636220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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