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Article

Temperature-sensitive growth and decreased thermotolerance associated with relA mutations in Escherichia coli.

Journal of bacteriology - 1 Oct 2003

Yang Xiaoming, Ishiguro Edward E

Abstract excerpt

The relA gene of Escherichia coli encodes guanosine 3',5'-bispyrophosphate (ppGpp) synthetase I, a ribosome-associated enzyme that is activated during amino acid starvation. The stringent response is thought to be mediated by ppGpp. Mutations in relA are known to result in pleiotropic phenotypes. We now report that three different relA mutant alleles, relA1, relA2, and relA251::kan, conferred...

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Identifiers

PMID: 13129947
DOI: 10.1128/JB.185.19.5765-5771.2003
PMCID: PMC193974

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Temperature-sensitive growth and decreased thermotolerance associated with relA mutations in Escherichia coli.PMID 13129947Read ↗

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