Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.

doi:10.1073/pnas.94.8.3823

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Article

Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1997

Keightley P D, Caballero A

Abstract excerpt

Theory concerning the evolution of sex and recombination and mutation load relies on information on rates and distributions of effects of deleterious mutations. Direct information on the genomic mutation rate in Drosophila implies that an accumulation of mildly deleterious mutations reduces viabi...

Topics

Animals
Caenorhabditis elegans
Drosophila
Genome
Mutation

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