Article
Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1997
Keightley P D, Caballero A
Abstract excerpt
Theory concerning the evolution of sex and recombination and mutation load relies on information on rates and distributions of effects of deleterious mutations. Direct information on the genomic mutation rate in Drosophila implies that an accumulation of mildly deleterious mutations reduces viability of populations by at least 1% per generation. We carried out an experiment to measure the deleterious mutation...
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