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Article

Neurotrophin-3 ameliorates sensory-motor deficits in Er81-deficient mice.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2006

Li L Y, Wang Z, Sedý J, Quazi R, Walro J M, Frank E, Kucera J

Abstract excerpt

Two factors, the ETS transcription factor ER81 and skeletal muscle-derived neurotrophin-3 (NT3), are essential for the formation of muscle spindles and the function of spindle afferent-motoneuron synapses in the spinal cord. Spindles either degenerate completely or are abnormal, and spindle afferents fail to project to spinal motoneurons in Er81 null mice; however, the interactions between ER81 and NT3 during the...

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Identifiers

PMID: 17013886
DOI: 10.1002/dvdy.20964
PMCID: PMC2587023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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