Article
Investigation of neuromuscular abnormalities in neurotrophin-3-deficient mice.
The European journal of neuroscience - 1 Jan 2010
Sheard Philip W, Bewick Guy S, Woolley Adele G, Shaw Jacqueline, Fisher Lorryn, Fong Sitt Wai, Duxson Marilyn J
Abstract excerpt
Neurotrophin-3 (NT-3) is a trophic factor that is essential for the normal development and maintenance of proprioceptive sensory neurons and is widely implicated as an important modulator of synaptic function and development. We have previously found that animals lacking NT-3 have a number of structural abnormalities in peripheral nerves and skeletal muscles. Here we investigated whether...
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