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Article

Pool-specific regulation of motor neuron survival by neurotrophic support.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Aug 2011

Lamballe Fabienne, Genestine Matthieu, Caruso Nathalie, Arce Vilma, Richelme Sylvie, Helmbacher Françoise, Maina Flavio

Abstract excerpt

The precise control of motor neuron (MN) death and survival following initial innervation of skeletal muscle targets is a key step in sculpting a functional motor system, but how this is regulated at the level of individual motor pools remains unclear. Hepatocyte growth factor (HGF) and its receptor Met play key developmental roles in both muscle and MNs. We generated mice (termed "Nes-Met") in which met is...

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Source

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Identifiers

PMID: 21813676
DOI: 10.1523/JNEUROSCI.2198-11.2011
PMCID: PMC6623376

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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