Article
A role for neuregulin1 signaling in muscle spindle differentiation.
Neuron - 19 Dec 2002
Hippenmeyer Simon, Shneider Neil A, Birchmeier Carmen, Burden Steven J, Jessell Thomas M, Arber Silvia
Abstract excerpt
The maturation of synaptic structures depends on inductive interactions between axons and their prospective targets. One example of such an interaction is the influence of proprioceptive sensory axons on the differentiation of muscle spindles. We have monitored the expression of three transcription factors, Egr3, Pea3, and Erm, that delineate early muscle spindle development in an assay of muscle spindle-inducing...
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