Article
Specificity and efficacy of dendritic cell-based vaccination against tuberculosis with complex mycobacterial antigens in a mouse model.
Tuberculosis (Edinburgh, Scotland) - 1 Mar 2007
Rubakova Elvira, Petrovskaya Svetlana, Pichugin Alexander, Khlebnikov Valentine, McMurray David, Kondratieva Elena, Baturina Irina, Kondratieva Tatiana, Apt Alexander
Abstract excerpt
Dendritic cells (DC) likely play important and unique roles in the generation of protective immunity to mycobacteria. In order to clarify their contributions, bone marrow-derived DC loaded with Mycobacterium tuberculosis sonicate antigens were used to stimulate T cell proliferation both in vitro...
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