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Article

Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro.

Journal of controlled release : official journal of the Controlled Release Society - 10 Dec 2014

Dewitte Heleen, Verbeke Rein, Breckpot Karine, Vandenbroucke Roosmarijn E, Libert Claude, De Smedt Stefaan C, Lentacker Ine

Abstract excerpt

Dendritic cell (DC)-based cancer vaccination has shown great potential in cancer immunotherapy. As a result, novel nanoparticles aiming to load DCs with tumor antigens are being developed and evaluated in vitro. For this, murine bone marrow-derived DCs (BM-DCs) are most commonly used as model DCs. However, many different protocols exist to generate these cells. Therefore, we investigated to what extent different...

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PMID: 24960224
DOI: 10.1016/j.jconrel.2014.06.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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