Article
Evaluation of energetic and dynamic coupling networks in a PDZ domain protein.
Journal of molecular biology - 1 Dec 2006
Fuentes Ernesto J, Gilmore Steven A, Mauldin Randall V, Lee Andrew L
Abstract excerpt
A number of computational and experimental studies have identified intramolecular communication "pathways" or "networks" important for transmitting allostery. Here, we have used mutagenesis and NMR relaxation methods to investigate the scope and nature of the communication networks found in the second post-synaptic density-95/discs large/zonula occludens-1 (PDZ) domain of the human protein tyrosine phosphatase 1E...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
