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Article

Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase.

Journal of virology - 1 Dec 1990

Air G M, Laver W G, Webster R G

Abstract excerpt

Monoclonal antibodies which inhibit influenza virus neuraminidase (NA) and which therefore indirectly neutralize virus infectivity bind to epitopes located on the rim of the active-site crater. The three-dimensional structure of one of these epitopes, recognized by monoclonal antibody NC41, has previously been determined (W. R. Tulip, J. N. Varghese, R. G. Webster, G. M. Air, W. G. Laver, and P. M. Colman, Cold...

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Identifiers

PMID: 1700825
DOI: 10.1128/JVI.64.12.5797-5803.1990
PMCID: PMC248733

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