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Article

Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes.

Journal of virology - 1 Aug 2000

Voeten J T, Bestebroer T M, Nieuwkoop N J, Fouchier R A, Osterhaus A D, Rimmelzwaan G F

Abstract excerpt

Viruses exploit different strategies to escape immune surveillance, including the introduction of mutations in cytotoxic T-lymphocyte (CTL) epitopes. The sequence of these epitopes is critical for their binding to major histocompatibility complex (MHC) class I molecules and recognition by specific CTLs, both of which interactions may be lost by mutation. Sequence analysis of the nucleoprotein gene of influenza A...

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Source

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Identifiers

PMID: 10888619
DOI: 10.1128/jvi.74.15.6800-6807.2000
PMCID: PMC112197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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