Article
Antibody epitopes on the neuraminidase of a recent H3N2 influenza virus (A/Memphis/31/98).
Journal of virology - 1 Dec 2002
Gulati Upma, Hwang Chi-Ching, Venkatramani Lalitha, Gulati Shelly, Stray Stephen J, Lee Janis T, Laver W Graeme, Bochkarev Alexey, Zlotnick Adam, Air Gillian M
Abstract excerpt
We have characterized monoclonal antibodies raised against the neuraminidase (NA) of a Sydney-like influenza virus (A/Memphis/31/98, H3N2) in a reassortant virus A/NWS/33(HA)-A/Mem/31/98(NA) (H1N2) and nine escape mutants selected by these monoclonal antibodies. Five of the antibodies use the same heavy chain VDJ genes and may not be independent. Another antibody, Mem5, uses the same V(H) and J genes with a...
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