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Article

Structure of antigenic sites on the haemagglutinin molecule of H5 avian influenza virus and phenotypic variation of escape mutants.

The Journal of general virology - 1 Oct 2002

Kaverin Nikolai V, Rudneva Irina A, Ilyushina Natalia A, Varich Natalia L, Lipatov Aleksandr S, Smirnov Yuri A, Govorkova Elena A, Gitelman Asya K, Lvov Dmitri K, Webster Robert G

Abstract excerpt

To elucidate the structure of the antigenic sites of avian H5 influenza virus haemagglutinin (HA) we analysed escape mutants of a mouse-adapted variant of the H5N2 strain A/Mallard/Pennsylvania/10218/84. A panel of five anti-H5 monoclonal antibodies (mAbs) was used to select 16 escape mutants. The mutants were tested by ELISA and haemagglutination inhibition with this panel of anti-H5 mAbs and the HA genes of the...

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PMID: 12237433
DOI: 10.1099/0022-1317-83-10-2497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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