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Article

Sequence variation in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes.

Virus research - 1 Jul 2004

Rimmelzwaan G F, Boon A C M, Voeten J T M, Berkhoff E G M, Fouchier R A M, Osterhaus A D M E

Abstract excerpt

CD8+ cytotoxic T lymphocytes (CTLs) contribute to the control of viral infections by recognizing peptides of viral proteins presented by MHC class I molecules on infected cells. Some viruses have developed strategies to evade recognition by CTL. One of these strategies involves antigenic variation in CTL epitopes as described for viruses chronically infecting their host like EBV, HIV, HBV and HCV. Here we show...

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Source

Identifiers

PMID: 15163496
DOI: 10.1016/j.virusres.2004.02.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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